Actionable Knowledge.

• Scientists are currently researching nearly 80 different types of inflammation, yet only a few are routinely monitored by a primary care doctor. There is not even complete agreement among scientists on what inflammation is on a cellular level. However, some consistently undesirable cellular consequences are associated with metabolic syndrome, obesity, and metabolic disease. These can be generally referred to as inflammation. We organize these undesirable cellular consequences into the following five types:

  1. Immunity Based
  2. Oxidative Stress Based
  3. Mitochondria Based
  4. Toxicity Based
  5. Hormone Based
• This chronic activation is where the immune system can significantly contribute to metabolic syndrome, obesity, and metabolic disease even before it has attacked tissue or caused inflammation. When you are low energy, achy all over, have a bit of brain fog, and feel a strong urge to be sedentary and eat sugary foods, you are severely disadvantaged in working to avoid and reverse metabolic syndrome, obesity, and metabolic disease.
• In the early stages of a leaky gut, the innate immune system primarily attacks the clearly non-human cells that don't belong outside the gut. This attack can consume a lot of energy, but at least it is highly localized and only happens in one area of the body. However, with all the non-human cells squeezing through the human cells of the bioreactor and colon wall, the adaptive immune system eventually gets involved because of the direct contact of human and non-human cells. One theory is that this contact transfers some of the proteins used to identify friend or foe. It starts mistaking human cells as foreign invaders. This mistaken identification is where really hard-to-fix problems arise.
• Threshold toxins in nutrition, bioreactor dysfunction, dysbiosis, and inactivity harm the body by hijacking five systems of the body that are otherwise essential to good health. It begins to become clear why metabolic syndrome, obesity, and metabolic disease are so complex to avoid and reverse in modern living. That's why Dr. Robert Lustig estimates over 80% of Americans are somewhere on the spectrum of metabolic syndrome, obesity, and metabolic disease.

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