Overview
There are more nerve cells in the enteric nervous system than in the central nervous system. That's right, there are more nerve cells in your digestive system than in your brain and they are just as busy and important. Further, other than consciousness, the enteric nervous system conducts almost all of the same complex command and control functions as the brain. That's why it's called the second brain.
From the moment you put something in your mouth, and it signals to activate the digestive system, until the food bolus enters the colon, and the bioreactor shuts down, it is at most 6 hours later. Therefore, the enteric nervous system is in full processing mode, doing everything it does for 6 hours after putting any food in your mouth. That's right, even one mouthful activates and requires the full processing and operation of the enteric nervous system for the full 6 hours.
Eating before sleeping has the same effect on the second brain as drinking a caffeinated beverage before bed has on the brain. If you eat a snack before bed at 10 p.m., your second brain's nerve cells don't get to start their Rest, Repair, and Recovery, or "sleep," until 6 hours later at 4 a.m. If you eat again at 8 a.m., your second brain only gets four hours of sleep. So how good do you think you'd feel and how healthy would you be only getting four hours sleep every night?
As the adverse effects of lack of sleep, overwork, and toxins accumulate, gastrointestinal motility generally slows down, further damaging the bioreactor and causing dysbiosis. The additional bioreactor damage and dysbiosis contribute to metabolic syndrome, obesity, and metabolic disease. Over the last few decades, we have steadily reduced the sleep (by late eating), increased the workload (by snacking), and increased the exposure to toxins (by factory food) of the enteric nervous system, bioreactor, and microbiome. It's a small wonder we have an epidemic of bioreactor dysfunction and dysbiosis leading to a metabolic syndrome, obesity, and metabolic disease crisis.